Oprah Reveals All Time Most Memorable Celebrities She Has Ever Interviewed

Tom Cruise

From Lance Armstrong admitting to using performance enhancing drugs to Rhianna's breakdown, Oprah has heard it all!

Here is our pick of Oprah's most memorable celebrity interviews...

Tom Cruise was crazy in love.

Tyler Perry

During this interview in 2005, we saw an excited Cruise professing his love for his now-wife Katie Holmes by jumping up and down on Oprah’s couch.

Tyler Perry's interview with Oprah was quite emotional. He admitted to being beaten and sexually abused as a child.

Ellen DeGeneres

Perry not only announced that he had suffered abuse from his father and multiple adults in his life, the show also filled its audience entirely with men who had similar stories to tell.

Ellen’s Coming Out Interview, 1997 was one of Oprah's most memorable. Ellen first revealed her sexuality on the cover of Time Magazine. In 1997, this Oprah episode generated a lot of controversy.

Lance Armstrong

Audience members criticized DeGeneres’s decision to come out of the closet. This was unheard of at the time but was a huge step forward towards equality in the media.

Lance Armstrong came clean about his use of performance enhancing drugs in 2013. Oprah sat down with the Tour de France champion to discuss his use openly.

Chris Rock

Winfrey approached the majorly controversial tv segment with her usual grace and compassion towards Armstrong.

Comedian Chris Rock has been one of Oprah’s favorite guests. He has appeared on her show numerous times. Rock and Oprah got up close and personal in 2009 while he was on the talk show to promote his documentary film Good Hair.

Celine Dion

Oprah surprisingly allowed Rock to run his hands through her hair to see if it was actually hers. The final verdict was that it was not, but everyone in the audience had a good laugh about it.

Another frequent guest on The Oprah Winfrey Show is Celine Dion. In 1997 Celine appeared on an episode that brought tears to the audience’s eyes. On the show, the vocal star performed her Oscar-nominated hit Because You Loved Me.

Sarah Furguson

Celine had no clue that Oprah invited Celine’s mother and father to the show, plus all 13 of her sisters and brothers! The entire family sang the song Celine’s mother wrote for her when she was a little girl, called It Was Only a Dream.

Sarah Ferguson begs for forgiveness after her huge bribery scandal. The Duchess of York appeared on the show right after being caught accepting a bribe from an undercover reporter in exchange for access to her ex-husband, Prince Andrew.

Barack Obama

This incident was a new low for Ferguson, and Winfrey got all the details.

Barack Obama appearance on the show threw Oprah for a loop.

Michael Jackson

Some people believe Winfrey’s support helped get him elected.

Michael Jackson gives Oprah a tour of the bizarre Neverland Ranch. He opened up to Oprah in 1993 for a worldwide audience of 90 million people.

Whitney Houston

He answered questions about sex and the lightening of his skin.

In 2009, the now deceased Houston broke her seven-year stretch of turning down interviews to appear with Oprah. Houston was very candid on the show opening up about things we had already suspected.

Rihanna

They talked about her drug abuse, her marriage to Bobby Brown being toxic, and that her vocal chords weren’t in good shape.

Rihanna broke down to Oprah over Chris Brown. The pop singer hadn’t talked about the notorious beat down by Brown very much.

John F. Kennedy

The interview showed that she wasn’t quite over him and really seemed confused about her feelings.

John F. Kennedy Jr.

Sidney Poitier

sat down for an interview with Oprah in 1996 for a highly coveted interview only three years before his untimely death from a plane crash.

Mackenzie Phillips

A lifelong inspiration for Oprah, Sidney Poitier surprised Oprah during her 20th anniversary special in 2005 with a passage he wrote especially for her.

On the Oprah Show, Mackenzie Phillips admitted to an incestuous relationship with her dad. Relations with her father, Mamas & the Papas member John Phillips, started with a drug-fueled rape at age 19.

Donny and Marie Osmond

This event moved into him offering to run away with her, and then ended 10 years later with a pregnancy and an abortion.

In 2007, Donny and Marie Osmond, along with an additional 124 members of the Osmond family, appeared onstage for a reunion.